12 days in Italy Itinerary

12 days in Italy Itinerary

Created using Inspirock Italy holiday planner

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Route & dates

12 days in Italy Itinerary

Start: Seattle
Fly:  16​h
1
Florence
— 2 nights
bus:  1​h 15​min
2
Siena
— 2 nights
Drive:  2​h 30​min
3
Rome
— 3 nights
Fly:  3​h 15​min
4
Venice
— 3 nights
Fly:  16​h 15​min
End: Seattle


Learn more about your trip

2
nights
Florence

Florence ©
Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
Florence is known for museums, historic sites, shopping, nightlife, and parks. Your plan includes some of its best attractions: explore the world behind art at Uffizi Galleries, admire the striking features of The Baptistery of St. John, take an in-depth tour of Basilica di Santa Croce, and take in panoramic vistas at Campanile di Giotto.

To see more things to do, other places to visit, and more tourist information, read Florence road trip planner .

Seattle, USA to Florence is an approximately 16-hour flight. You can also do a combination of flight and train; or do a combination of shuttle and flight. You'll lose 9 hours traveling from Seattle to Florence due to the time zone difference. While traveling from Seattle, expect a bit warmer days and about the same nights in Florence, ranging from highs of 78°F to lows of 59°F. Finish your sightseeing early on the 4th (Wed) so you can take a bus to Siena.

Things to do in Florence

Museums Historic Sites Parks
Find places to stay Sep 2 — 4:
Highlights from your plan
Gallerie Degli Uffizi ©
Gallerie Degli Uffizi
Academy Of Florence Art Gallery ©
Academy Of Florence Art Gallery
Piazzale Michelangelo ©
Piazzale Michelangelo

2
nights
Siena

Siena, a medieval Tuscan city, features numerous attractions, including a historic town center, alleyways, towers, and well-preserved buildings.
Kick off your visit on the 5th (Thu): awaken your taste buds at some of the top wineries in the area. Get ready for a full day of sightseeing on the 6th (Fri): make a trip to Piazza del Campo, take in the architecture and atmosphere at Siena Cathedral, then get lost in a book at Biblioteca Piccolomini, and finally explore the historical opulence of Palazzo Pubblico and Museo Civico.

For reviews, where to stay, and other tourist information, read our Siena trip planning site .

You can take a bus from Florence to Siena in 1.5 hours. Alternatively, you can drive; or take a train. September in Siena sees daily highs of 81°F and lows of 61°F at night. Wrap up your sightseeing on the 6th (Fri) to allow time to drive to Rome.

Things to do in Siena

Tours Historic Sites Museums
Find places to stay Sep 4 — 6:
Highlights from your plan
Wine Tours & Tastings
Piazza del Campo ©
Piazza del Campo
Duomo di Siena ©
Duomo di Siena

3
nights
Rome

Rome ©
Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
Rome is known for historic sites, nightlife, museums, classes, and shopping. Your plan includes some of its best attractions: delve into the distant past at Colosseum, make a trip to Roman Forum, admire the masterpieces at Vatican Museums, and admire the landmark architecture of Pantheon.

Ask Inspirock to suggest an itinerary and make planning a trip to Rome fast, fun, and easy.

Drive from Siena to Rome in 2.5 hours. Alternatively, you can take a bus; or take a train. In September in Rome, expect temperatures between 81°F during the day and 60°F at night. Finish your sightseeing early on the 9th (Mon) to allow enough time to travel to Venice.

Things to do in Rome

Historic Sites Museums Neighborhoods

Side Trip

Vatican City
Find places to stay Sep 6 — 9:
Highlights from your plan
Colosseum ©
Colosseum
Pantheon ©
Pantheon
St. Peter's Basilica ©
St. Peter's Basilica

3
nights
Venice

Venice ©
Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.
Venice is known for historic sites, nature, museums, nightlife, and shopping. Your plan includes some of its best attractions: contemplate the waterfront views at Canal Grande, take in the views from Ponte di Rialto, contemplate the long history of Ponte dei Sospiri, and don't miss a visit to St. Mark's Square.

To see other places to visit, photos, ratings, and tourist information, read Venice attractions planner.

Traveling by flight from Rome to Venice takes 3.5 hours. Alternatively, you can take a train; or drive. In September, plan for daily highs up to 77°F, and evening lows to 59°F. Cap off your sightseeing on the 12th (Thu) early enough to travel back home.

Things to do in Venice

Historic Sites Museums Tours
Find places to stay Sep 9 — 12:
Highlights from your plan
Canal Grande ©
Canal Grande
Basilica di San Marco
Basilica di San Marco
Piazza San Marco ©
Piazza San Marco

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