16 days in Northwest Italy Itinerary

Created using Inspirock Italy trip planner
Make it your trip
Fly
1
Rome
— 2 nights
Fly
2
Cinque Terre
— 3 nights
Drive
3
Florence
— 3 nights
Drive
4
Siena
— 3 nights
Drive
5
Montepulciano
— 2 nights
Drive
6
Rome
— 1 night
Fly

S M T W T F S
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
3
4
5
6

Rome — 2 nights

Eternal City

Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
Kick off your visit on the 16th (Sun): pause for some serene contemplation at Church of St. Louis of the French, browse the exhibits of Museo Nazionale di Castel Sant'Angelo, then don't miss a visit to Cupola di San Pietro, and finally indulge your taste buds at Food & Drink. Get ready for a full day of sightseeing on the next day: stroll the grounds of Catacombs of Saint Callixtus, test your team's savvy at popular escape rooms, then appreciate the history behind Monumento a Vittorio Emanuele II, and finally contemplate in the serene atmosphere at Basilica Papale di Santa Maria Maggiore.

Plan my Rome trip by asking Inspirock to come up with tips and suggestions.

Cleveland, USA to Rome is an approximately 14-hour flight. The time zone difference when traveling from Cleveland to Rome is 6 hours. Plan for a bit warmer temperatures traveling from Cleveland in April, with highs in Rome at 69°F and lows at 49°F. Cap off your sightseeing on the 17th (Mon) early enough to catch the flight to Cinque Terre.
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Side Trip
Find places to stay Apr 15 — 17:

Cinque Terre — 3 nights

Italian Riviera

Made up of five picturesque towns on the Ligurian coast, Cinque Terre is Italy's answer to the French Riviera.
Bring the kids along to Angelo's Boat Tours - Cinque Terre Boat Tours and Footpath Monterosso - Vernazza. Change things up with these side-trips from Cinque Terre: Porto Venere (San Pietro Church & Portovenere) and Parco Naturale Regionale di Porto Venere (in La Spezia). The adventure continues: explore the wealth of natural beauty at Parco Nazionale Cinque Terre, don't miss a visit to Oratorio della Confraternita dei Neri Mortis et Orationis, get to know the fascinating history of Groppo, and hike along Cinque Terre Trails.

To see photos, other places to visit, traveler tips, and other tourist information, you can read our Cinque Terre holiday maker website.

Getting from Rome to Cinque Terre by flight takes about 3 hours. Other options: take a train; or drive. In April, daytime highs in Cinque Terre are 66°F, while nighttime lows are 47°F. Finish up your sightseeing early on the 20th (Thu) so you can go by car to Florence.
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Find places to stay Apr 17 — 20:

Florence — 3 nights

Birthplace of the Italian Renaissance

Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
Family-friendly places like Cathedral of Santa Maria del Fiore and Florence Academy of Fine Arts will thrill your kids. Next up on the itinerary: don't miss a visit to Piazzale Michelangelo, ponder the world of politics at Palazzo Vecchio, take in the views from Ponte Vecchio, and admire the striking features of The Baptistery of St. John.

You can plan Florence trip in no time by asking Inspirock to help create your itinerary.

Traveling by car from Cinque Terre to Florence takes 2.5 hours. Alternatively, you can take a train. Expect a daytime high around 67°F in April, and nighttime lows around 50°F. Finish your sightseeing early on the 23rd (Sun) to allow enough time to drive to Siena.
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Find places to stay Apr 20 — 23:

Siena — 3 nights

Cultural Heart of Tuscany

Siena, a medieval Tuscan city, features numerous attractions, including a historic town center, alleyways, towers, and well-preserved buildings.
Start off your visit on the 24th (Mon): steep yourself in history at Palazzo Chigi Saracini, take in panoramic vistas at Torre del Mangia, steep yourself in history at Centro Storico di Siena, pause for some serene contemplation at Duomo di Siena, then admire the masterpieces at Museo dell'Opera Metropolitana, and finally steep yourself in history at Battistero di San Giovanni. Get ready for a full day of sightseeing on the next day: indulge in some culinary diversions at a local gastronomic tour, then step into the grandiose world of Palazzo Pubblico and Museo Civico, and then don't miss a visit to Piazza del Campo.

To find traveler tips, ratings, other places to visit, and more tourist information, use the Siena trip tool.

Drive from Florence to Siena in 1.5 hours. Alternatively, you can take a bus; or take a train. Expect a daytime high around 68°F in April, and nighttime lows around 47°F. Wrap up your sightseeing on the 26th (Wed) to allow time to drive to Montepulciano.
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Find places to stay Apr 23 — 26:

Montepulciano — 2 nights

Pearl of the 16th Century

Perched on a limestone ridge in the heart of Tuscany, Montepulciano is known worldwide for its production of red wine, the Vino Noble.
On the 26th (Wed), get to know the fascinating history of Centro storico, contemplate in the serene atmosphere at Dome of Montepulciano, make a trip to Piazza Grande a Montepulciano, make a trip to Terrazza Del Palazzo Comunale, then shop like a local with Quinteaquadri Lab Gallery, and finally contemplate in the serene atmosphere at Tempio di San Biagio. Keep things going the next day: make a trip to Piazza Pio II, admire the verdant scenery at Val d'Orcia, then contemplate the long history of Abbazia di Sant'Antimo, then relax and rejuvenate at some of the best spas, and finally take in the spiritual surroundings of Parrocchia Santissimo Nome Di Gesu'.

Take the guesswork out of planning a Montepulciano vacation by using our trip itinerary maker.

Drive from Siena to Montepulciano in an hour. Alternatively, you can take a train; or take a bus. In April, plan for daily highs up to 68°F, and evening lows to 47°F. Finish your sightseeing early on the 28th (Fri) to allow enough time to drive to Rome.
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Find places to stay Apr 26 — 28:

Rome — 1 night

Eternal City

Start off your visit on the 28th (Fri): get to know the fascinating history of Piazza Navona, admire the local landmark of Trevi Fountain, delve into the distant past at Pantheon, then contemplate the long history of St. Peter's Basilica, and finally explore the ancient world of Colosseum. Get ready for a full day of sightseeing on the 29th (Sat): explore the ancient world of Palatine Hill, then explore the world behind art at Vatican Museums, and then explore the engaging exhibits at Welcome To Rome.

To find maps, reviews, more things to do, and tourist information, use the Rome tour planner.

You can drive from Montepulciano to Rome in 2 hours. Other options are to take a train; or take a bus. Wrap up your sightseeing on the 29th (Sat) early enough to fly back home.
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Historic Sites · Museums · Childrens Museums
Side Trip
Find places to stay Apr 28 — 29: