23 days in Rome, Tuscany & Nice Itinerary

23 days in Rome, Tuscany & Nice Itinerary

Created using Inspirock Europe route planner
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Make it your trip
Fly
1
Rome, Italy
— 6 nights
Drive
2
Siena, Italy
— 3 nights
Drive
3
Florence, Italy
— 5 nights
Drive
4
Pisa, Italy
— 1 night
Drive
5
Nice, France
— 7 nights
Fly

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Rome, Italy — 6 nights

Eternal City

Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
Rome is known for historic sites, sightseeing, and nightlife. Your trip includes some of its best attractions: pause for some serene contemplation at St. Peter's Basilica, admire the masterpieces at Galleria Borghese, contemplate the long history of Roman Forum, and delve into the distant past at Pantheon.

To see other places to visit, where to stay, traveler tips, and other tourist information, read our Rome trip itinerary maker website.

Weston, USA to Rome is an approximately 13.5-hour flight. You can also do a combination of car and flight. The time zone changes from Eastern Standard Time to Central European Standard Time, which is usually a 6 hour difference. Traveling from Weston in September, plan for somewhat warmer nights in Rome, with lows around 60°F. Finish up your sightseeing early on the 8th (Wed) so you can go by car to Siena.
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Historic Sites · Museums · Neighborhoods · Tours
Side Trip
Find places to stay Sep 2 — 8:

Siena, Italy — 3 nights

Cultural Heart of Tuscany

Siena, a medieval Tuscan city, features numerous attractions, including a historic town center, alleyways, towers, and well-preserved buildings.
You'll find plenty of places to visit near Siena: San Gimignano (Torre Grossa, Guardastelle Vineyard, &more). There's lots more to do: indulge your senses at some of the top wineries in the area, admire the masterpieces at Palazzo Pubblico and Museo Civico, don't miss a visit to Piazza del Campo, and pause for some serene contemplation at Basilica Cateriniana San Domenico.

To find where to stay, reviews, maps, and more tourist information, refer to the Siena trip itinerary app.

Getting from Rome to Siena by car takes about 2.5 hours. Other options: take a bus; or take a train. Expect a daytime high around 81°F in September, and nighttime lows around 61°F. Cap off your sightseeing on the 11th (Sat) early enough to go by car to Florence.
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Wineries · Historic Sites · Tours · Museums
Side Trip
Find places to stay Sep 8 — 11:

Florence, Italy — 5 nights

Birthplace of the Italian Renaissance

Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
Dedicate the 16th (Thu) to wine at some of the top wineries in the area. There's still lots to do: don't miss a visit to Piazzale Michelangelo, steep yourself in history at Basilica of Santa Croce, pause for some photo ops at Campanile di Giotto, and explore the world behind art at Pitti Palace.

To see other places to visit, more things to do, traveler tips, and other tourist information, refer to the Florence trip planning website.

You can drive from Siena to Florence in 1.5 hours. Alternatively, you can take a bus; or take a train. Expect a daytime high around 78°F in September, and nighttime lows around 59°F. Wrap up your sightseeing on the 16th (Thu) to allow time to drive to Pisa.
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Historic Sites · Tours · Wineries · Museums
Find places to stay Sep 11 — 16:

Pisa, Italy — 1 night

Known worldwide for the Leaning Tower of Pisa, the city of Pisa historically served as a maritime power in the heart of Tuscany.
Start off your visit on the 17th (Fri): contemplate the long history of Le mura di Lucca, then admire the striking features of St Martin Cathedral, then examine the collection at Museo Aviotruppe Esercito Italiano, and finally make a trip to Leaning Tower of Pisa.

To find more things to do, where to stay, and more tourist information, you can read our Pisa road trip website.

Getting from Florence to Pisa by car takes about 1.5 hours. Other options: take a bus; or take a train. In September, daily temperatures in Pisa can reach 78°F, while at night they dip to 59°F. Finish your sightseeing early on the 17th (Fri) so you can drive to Nice.
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Historic Sites · Museums
Side Trip
Find places to stay Sep 16 — 17:

Nice, France — 7 nights

Nissa la Bella (Nice the Beautiful)

Well-known for the beautiful views of its famous Promenade des Anglais waterfront, Nice is an ethnically-diverse coastal port city on the French Riviera and the fifth most populated city in France.
Explore Nice's surroundings by going to Chapelle de Saint-Cassien des Bois (in Tanneron), Cannes (Galerie1414, Lérins Islands, &more) and Musee Picasso (in Antibes). There's much more to do: indulge your senses at Azur Wine Tours, take in nature's colorful creations at Le Jardin Exotique d'Eze, don't miss a visit to Promenade des Anglais, and get great views at Colline du Chateau overlook.

To find out how to plan a trip to Nice, use our trip itinerary maker.

You can drive from Pisa to Nice in 4 hours. Alternatively, you can take a train; or fly. Plan for somewhat warmer nights when traveling from Pisa in September since evenings lows in Nice dip to 65°F. Finish your sightseeing early on the 24th (Fri) so you can travel back home.
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Historic Sites · Neighborhoods · Tours · Parks
Side Trips
Find places to stay Sep 17 — 24:

Tuscany travel guide

4.4
Landmarks · Art Museums · Sacred & Religious Sites
Birthplace of the Italian Renaissance
Known for its landscapes, traditions, and history, Tuscany possesses an unparalleled artistic legacy that continues to influence world culture. Regarded as the birthplace of the Italian Renaissance, the region boasts a lengthy list of attractions, including world-class museums, art galleries, and archeological sites. With a distinct culture and a very strong linguistic identity, this region is sometimes referred to as a nation within a nation. A land of picture-postcard areas, Tuscany contains plenty of places to visit on your holiday, with seven World Heritage Sites, including the historic town centers of Florence and Siena. With more than 120 protected nature preserves, Tuscany is not only a land of culture and historic monuments, but also a great place to discover and enjoy the Italian outdoors. Take it slowly here (as the locals do), and give yourself plenty of time to get to know the local culture and cuisine of Tuscany's medieval towns and ancient villages.
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